By Professor Michael Selzer, Professor Stephanie Clarke, Dr Leonardo Cohen, Gert Kwakkel, Robert Miller
In freestanding volumes, the Textbook of Neural fix and Rehabilitation offers complete insurance of the technological know-how and perform of neurological rehabilitation. Revised all through, bringing the booklet absolutely brand new, this quantity, Neural fix and Plasticity, covers the elemental sciences correct to restoration of functionality following damage to the anxious method, reviewing anatomical and physiological plasticity within the general primary fearful process, mechanisms of neuronal dying, axonal regeneration, stem telephone biology, and study recommendations distinctive at axon regeneration and neuron alternative. New chapters were further protecting pathophysiology and plasticity in cerebral palsy, stem cellphone remedies for mind problems and neurotrophin fix of spinal wire harm, in addition to various others. Edited and written via top foreign experts, it truly is a necessary source for neuroscientists and gives a starting place for the paintings of medical rehabilitation pros.
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Extra info for Textbook of Neural Repair and Rehabilitation: Volume 1, Neural Repair and Plasticity
It is divided into two sections. Section A, Neural plasticity, includes chapters on the morphological and physiological plasticity of neurons that underlie the ability of the nervous system to learn, accommodate to altered patterns of use, and adapt to injury. Section B, Neural repair, includes chapters on the neuronal responses to injury, stem cells and neurogenesis in the adult CNS, the molecular mechanisms inhibiting and promoting axon regeneration in the CNS, and strategies to promote cell replacement and axon regeneration after injury, the design of prosthetic neural circuitry, and translational research, applying animal experimental results to human patients.
The titles of the included publications were then checked for appropriateness. such as aphasia, apraxia, visual agnosia, or neglect, have been identified in the second half of the 19th and the first half of the 20th century. Many of the original reports described the course of spontaneous recovery and proposed specific rehabilitative measures. During the last 25 years the field of rehabilitation of cognitive functions has expanded rapidly. The annual number of publications concerning neuropsychological rehabilitation, including aphasia therapy, has increased from about 100 in 1980 to over 500 in 2004, with a steep increase beginning around 1987 (Fig.
First, the degree of atrophy and degeneration is greatest if axons are damaged proximal to the cell body than if the injury occurs more distally. Second, retrograde atrophy and degeneration is more likely if a substantial proportion of the projections to target cells are interrupted. This is thought to reflect the fact that retrograde atrophy and degeneration occur because neurons depend on trophic factors supplied by the target (the topics of neuronal death and rescue and the role of target-derived trophic factors are considered elsewhere in this volume, see Volume I, Chapter 16 by Gould and Oppenheim).