Download Myelodysplastic Syndromes: Clinical and Biological Advances by Peter L. Greenberg PDF

By Peter L. Greenberg

This publication describes the scientific type, underlying organic mechanisms and remedy of the myelodysplastic syndromes. Authored by way of foreign specialists, the chapters disguise all facets of the myelodysplastic syndromes, from an in-depth research of the multifactorial nature of this ailment, together with an evaluate of stromal, immunological and stem telephone abnormalities, to a assessment of contemporary molecular and cytogenetic discoveries and insights. This publication could be a important source to clinicians and researchers who desire to study extra approximately myelodysplastic syndromes.

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Extra resources for Myelodysplastic Syndromes: Clinical and Biological Advances

Sample text

1994). The chronic myeloid leukemias: guidelines for distinguishing chronic granulocytic, atypical chronic myeloid, and chronic myelomonocytic leukemia. Br. J. , 87, 746. 5. , Diebold, J. et al. (1999). WHO classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting – Airlie House, Virginia, November 1997. J. Clin. , 17, 3835–49. 6. Bennett, J. M. (2000). WHO classification of the acute leukemias and myelodysplastic syndrome.

Application of different prognostic scoring systems and comparison of the FAB and WHO classifications in Korean patients with myelodysplastic syndrome. Leukemia, 17, 305–13. 66. , and Michalova, K. (2004). Combined stratification of refractory anemia according to both WHO and IPSS criteria has a prognostic impact and improves identification of patients who may benefit from stem cell transplantation. Leuk. , 28, 551–7. 67. Nevill, T. , Shepherd, J. D. et al. (1998). Cytogenetic abnormalities in primary myelodysplastic syndrome are highly predictive of outcome after allogeneic bone marrow transplantation.

2004). High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia. Blood, 103, 2316–24. 105. Shih, L. , Wang, P. N. et al. (2004). Internal tandem duplication of fms-like tyrosine kinase 3 is associated with poor outcome in patients with myelodysplastic syndrome. Cancer, 101, 989–98. 106. Ohyashiki, J. , Yahata, N. et al. (1999). Telomere stability is frequently impaired in high-risk groups of patients with myelodysplastic syndromes.

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