By Harald Klaus Theml, Heinz Diem, Torsten Haferlach
A Flexibook for either the professional and non-specialist, the new e-book deals available info on hematology in a succinct structure. as well as supplying easy technique, the ebook makes use of greater than 260 colour illustrations to element the main up to date scientific systems. various tables and movement charts are incorporated to aid in differential analysis, making this a useful didactic reference for nurses, training physicians and citizens getting ready for board examinations.
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Extra info for Color Atlas of Hematology. Practical and Clinical Diagnosis
It should be noted that too much blood in the bone marrow sample will impede the semiquantitative analysis. In addition to this type of smear, squash preparations should also be prepared from the bone marrow material for selective staining. To do this, a few small pieces of bone marrow are placed on a slide and covered by a second slide. The two slides are lightly pressed and slid against each other, then separated (see Fig. 6). The smears are allowed to air-dry and some are incubated with panoptic Pappenheim staining solution (see previous text).
The use of nuclear appendages to determine gender has lost significance in favor of genetic testing. Theml, Color Atlas of Hematology © 2004 Thieme All rights reserved. Usage subject to terms and conditions of license. Note the granulations, inclusions, and appendages in segmented neutrophilic granulocytes e f g h Fig. 13 continued. e Hypersegmented neutrophilic granulocyte (six or more segments). There is an accumulation of these cells in megaloblastic anemia. f Drumstick (arrow 1) as an appendage with a thin filament bridge to the nucleus (associated with the X-chromosome), adjoined by a thrombocyte (arrow 2).
The nuclei slowly take on a kidney bean shape and have some plasticity. Metamyelocytes are unable to divide. From this stage on, only further maturation of the nucleus occurs by contraction, so that the distinctions (between metamyelocytes, band neutrophils, and segmented neutrophils) are merely conventional, although they do relate to the varying “maturation” of these cell forms. Diagnostic Implications. Like their precursors, myelocytes and metamyelocytes normally appear in the peripheral blood only during increased cell production in response to stress or triggers, especially infections (for an overview of possible triggers, see p.