Download Advances in Neurochemistry: Volume 3 by Neil Raymond Sims, Patrick Robert Carnegie (auth.), B. W. PDF

By Neil Raymond Sims, Patrick Robert Carnegie (auth.), B. W. Agranoff, M. H. Aprison (eds.)

The unique premise of the Editors in starting up this sequence used to be that there existed a readership ofneurochemists with significant biochemical again­ floor who could utilize a chain devoted to either new advance­ ments and really expert reports in neurochemistry. Having chosen our authors, we've got provided them almost whole freedom to mirror and speculate in a box within which they've got accomplished prominence. The reaction to the 1st volumes has been lucrative. the current one keeps during this culture. whereas we haven't tried to put up really good volumes, the current quantity includes just a little comparable chapters (Chapters four and five, at the position of amino acid neurotransmitters). the 1st 3 chapters research 3 various ways, every one of present curiosity, in neurochemi­ cal ways to the molecular bases of neuronal and glial constitution. B. W. Agranoff M. H. Aprison vii CONTENTS bankruptcy 1 2',3'-CYCUC NUCLEOTIDE 3'-PHOSPHODIESTERASE NEIL RAYMOND SIMS AND PATRICK ROBERT CARNEGIE 1. creation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. Assay of CNPase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . three 2. 1. want for Activation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . three 2. 2. comparability of Assays . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . three three. organization of CNPase with Myelin . . . . . . . . . . . . . . . . . . . . . . . 7 three. 1. ancient. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 three. 2. Subcellular Fractionation. . . . . . . . . . . . . . . . . . . . . . . . . . . . eight three. three. improvement. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . eight three. four. Mutant Mice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . nine three. five. Use as a Myelin Marker . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 three. 6. Myelin-Related Fractions and Peripheral Nerve Myelin. eleven four. CNPase in Nonmyelin Fractions. . . . . . . . . . . . . . . . . . . . . . . . . . thirteen five. Activation and Isolation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . thirteen five. 1. creation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . thirteen five. 2. Activation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 five. three. Solubilization and Fractionation. . . . . . . . . . . . . . . . . . . . . . 15 6. houses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 6. 1. Substrate Specificity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE 41 Wysocki, S. , 1972, Influence of thyroid hormones on enzyme activities of myelinating rat central nervous tissues, Eur. J. Biochem. 28:183-189. Zanetta, J. , and Morgan, I. , 1972, The presence of2',3'-cycIic AMP 3'-phosphohydrolase in glial cells in tissue culture, J. Neurochem. 19:881-883. Zimmerman, A. , Quarles, R. , Webster, H. , and Brady, R. , 1975, Characterization and protein analysis of myelin subfractions in rat brain: Developmental and regional comparisons, J.

25: 19-27. Volpe, J. , Marasa, J. , and Agrawal, H. , 1975, Relation ofC-6glial cells in culture to myelin, Biochem. J. 152:701-703. Waehneldt, T. , 1975, Ontogenetic study of a myelin-derived fraction with 2' ,3 '-cyclic nucleotide 3'-phosphohydrolase activity higher than that of myelin, Biochem. J. 151:435437. Waehneldt, T. , 1972, Isolation of rat brain myelin, monitored by polyacrylamide gel electrophoresis of dodecyl sulfate-extracted proteins, Brain Res. 40:419-436. Wassenaar, J. , and Kroon, A.

1964, Mutant mice (Quaking and Jimpy) with deficient myelination in the central nervous system, Science 144:309-311. Simons, S. , and Johnston, P. , 1976, Prenatal and postnatal protein restriction in the rat: Effect of some parameters related to brain development, and prospects for rehabilitation, J. Neurochem. 27:63-69. Sims, N. , and Carnegie, P. , 1975, Release of2' ,3'-cyclic nucleotide 3'-phosphohydrolase 40 CHAPTER 1 from myelin: A useful model of membrane protein solubilisation, Proc.

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